KLF4 also known as gut-enriched Kruppel-like factor (GKLF) acts as a transcriptional activator or repressor depending on the promoter context and/or cooperation with other transcription factors.

OCT4 is a mammalian POU transcription factor expressed by early embryo cells and germ cells. It belongs to the POU transcription factor family.

Nanog also known as Homeobox transcription factor Nanog is a homeobox transcription factor belonging to the Nanog homeobox family with a homeobox DNA-binding domain.

SOX2 belongs to a family of DNA binding High-Mobility group domain transcription factor proteins, which has been identified as a key player in both in regulating embryonic development as well as in determining cell fates.

Toll-like receptor 9 (TLR9) often known as CD289 (cluster of differentiation 289), is a member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern.

Toll-like receptor 8 (TLR8) often designated as CD288 (cluster of differentiation 288) is a member of evolutionarily conserved Toll-like receptor family which are critical parts of the evolutionarily conserved innate immune system.

Toll-like receptor 7 (TLR7), is an immune gene possessed by humans, other mammals and additionally in avian species playing a significant role in initiating antiviral immune responses.

Toll-like receptor 6 (TLR6) often designated as CD286 (cluster of differentiation 286), is a member of the Toll-like receptor family, a highly conserved series of ancient innate immune pattern recognition receptors.

Toll-like receptor 5 (TLR5), a member of the evolutionarily conserved Toll-like receptor family, has evolved to permit mammals specifically to detect flagellated bacterial pathogens.

Toll-like receptor 4 (TLR4) often designated as CD284 (cluster of differentiation 284) is a class I transmembrane receptor belonging to the large homologous family of Toll like receptors.

Toll-like receptor 3 (TLR3) often designated as CD283 (cluster of differentiation 283) is a type I transmembrane receptor protein.

Toll-like receptor 2 (TLR2), often designated as CD282 (cluster of differentiation 282) is a type I transmembrane protein belonging to the large homologous family of Toll like receptors.

Folates play an important role in protein and nucleic acid biosynthesis and are particularly recognized for their roles in spinal canal and brain development during early pregnancy.

Neuropilin-1 (Nrp-1) was recently identified as a possible surface marker for naturally occurring CD4+CD25+ regulatory T cells and is constitutively expressed on the cell irrespective of its activation status.

Tumor metastasis plays a key role in assessing treatment strategies and an important factor in determining patient prognosis. Not surprisingly, significant effort has been focused on elucidating the molecular basis behind tumor metastasis.

Flow cytometric analysis of intracellular FOXP3 (IMG-5802D) and cell surface FR4 with clone 12A5 (IMG-6217C) (left) and clone TH6 (IMG-6218C) (right) at 0.06 ug/10^6 mouse splenocytes.

Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein.

Toll-like receptor 1 (TLR1) often designated as CD281 (cluster of differentiation 281), a member of the Toll-like receptor family recognizes pathogen-associated molecular pattern with specificity for gram-positive bacteria.

Learn about the features and characteristics of good electronic parts and components and the best ways to find them.

BREAKING NEWS

Surgery on a beating heart? A doctor in America operating on a patient in France? Surgical robots are making this and other amazing medical feats possible.

These robots help doctors make smaller incisions and perform complex operations with greater motion control. How?

Enthu to know what's happening ,scroll eyes downwards.....

Substantial improvements in the art and science of surgery were made over the 150 years since the introduction of antiseptic techniques by Lister, including improved anesthetic agents, antibiotics, surgical nutrition, and organ transplantation,in which the basic tools and techniques remained basically unchanged. The core task of "surgery,"that is, "cutting and sewing," with hand instruments and direct visualization of and contact with the organ or tissue has remained the same. However, during the last quarter of the 20th century, and especially during the last decade, there has been a paradigm shift in the methods for performance of surgery. For many procedures, the "invasiveness" involved has been dramatically reduced resulting in superior outcomes manifested as improved survival, fewer complications, and quicker return to functional health and productive life. This focus on less or "minimal" invasiveness has gained momentum and has been the subject of intense investigation in recent years.